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What is gluten sensitivity? Gluten sensitivity is one of the types of allergies that affect the digestive system, as it may damage some organs in the body. Through our following lines on the reference website, we highlight to you the concept of gluten sensitivity, its symptoms and causes, and the most prominent complications that occur when suffering from gluten sensitivity.

gluten

Gluten is known as a complex natural mixture that is not dissolved in water, as it is found in some plants, examples of which are: wheat, barley and oats, as this mixture consists mainly of gliadin and gluten proteins, which are considered the basis for causing symptoms of gluten sensitivity, and gluten constitutes 90 % of the total proteins that are found in the wheat grain, and there are also types of gluten, and their difference is due to the sulfur content and the molecular weight within the gluten mixture.[1]

The importance of healthy gluten

Gluten is closely related to wheat and popular foods, as the media report the seriousness of the symptoms of gluten sensitivity and its complications, while there are many health results that benefit the human body due to the presence of gluten, based on research, and the following will be shown on the health importance of protein for the human body:[2]

  • Studies have shown that there is no association between long-term protein consumption and its risk to heart health, as a study was conducted in 2017 on many people who were in good health and did not suffer from any disease related to gluten, as this showed the risk of leaving gluten on heart health. .
  • Some studies have shown an association between wheat consumption and its positive health outcomes, as it was compared between people who consume large amounts of wheat that contains gluten, and people who eat small amounts of wheat, and the result was that people who consume large amounts of gluten have a lower risk of disease. Heart, diabetes and even deaths.
  • Studies have shown that gluten is one of the substances that stimulate the growth of beneficial bacteria in the gastrointestinal tract, in addition to that wheat bran contains the sugar araboxilan, which stimulates the beneficial bacteria in the colon.

What is gluten sensitivity?

Gluten sensitivity is defined as a A group of disorders that occur in the digestive system due to eating foods containing gluten, Where the body becomes unable to tolerate gluten in food, and it is also considered a case of self-response that the body shows and results in symptoms such as itching and others. Many important substances, and there is a type that does not affect the cells of the intestinal wall, but shows some digestive symptoms. These two types are called celiac disease and non-celiac gluten sensitivity, as they will be explained in the following:[3][4]

celiac disease

It is one of the diseases related to the appearance of symptoms of gluten sensitivity, as this disease occurs due to an abnormal immune response to gluten and the substances that contain it, as this disease works to damage the intestinal villi as it prevents the small intestine from absorbing nutrients, which leads to Malnutrition and low bone density, as well as abortion and infertility, may lead to the emergence of several diseases, and in the beginning, some neurological diseases and some types of cancer appear.[3]

Gluten sensitivity not associated with celiac disease

It is one of the newly discovered diseases related to gluten, as it is defined as a physical disorder related to the manifestation of symptoms of gluten sensitivity, and there is difficulty in explaining the mechanism of occurrence of the disease, but the contribution of wheat components in causing the disease has not been confirmed, and when referring to the intestinal wall it does not show any One of the symptoms of gluten sensitivity, where there are suggestions showing the role of inhibitors of the enzyme trypsin amylase, which works to stimulate the innate immune system, which leads to the emergence of these symptoms.[4]

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Symptoms of gluten sensitivity

There are many reasons that lead to the occurrence of gluten sensitivity, as cases are not similar in symptoms and some cases may appear symptomatic, while other cases may show a number of symptoms, and the following will explain these symptoms:[5]

  • Digestive problems: Where it is considered that this symptom is one of the main and main symptoms of gluten sensitivity, it includes diarrhea and constipation in addition to esophageal reflux and abdominal pain, and these symptoms vary in severity from person to person, as patients with irritable bowel have symptoms similar to symptoms Gluten sensitivity and improvement may be seen when gluten is stopped.
  • headache: The headache that affects patients with gluten sensitivity is similar to the feeling of roads, and some patients may feel migraine headaches, especially those with celiac disease.
  • Tingling and numbness: In this case, the person feels permanent tingling and tingling in the extremities, as this happens due to a disorder in the nerves of the hand and foot and may develop until there is numbness in the leg or shoulder, as this condition occurs in 50% of cases of intestinal disorder and is the cause of Unknown incidence in unrelated gluten sensitivity in celiac disease.
  • rash: Where gluten sensitivity shows red bumps that cause itching, and people with gluten sensitivity are more likely to develop psoriasis and eczema.
  • brain fog They are people who have difficulty concentrating and short-term memory loss. In this case, the patient suffers from interruptions in the sequence of thoughts when speaking or writing, and he also finds himself disoriented and lacking a sense of his surroundings.

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Causes of gluten sensitivity

Gluten sensitivity is an allergic reaction to foods that contain gluten. When a person is exposed to these foods, it stimulates the immune system by causing allergic reactions after eating gluten sources. Foods that contain gluten include:[6]

  • Wheat.
  • the bread.
  • rye
  • barley.
  • Pasta.
  • flour;
  • bulgur
  • couscous.
  • white buckwheat;
  • Some types of oats.

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Complications of gluten sensitivity

There are many serious complications that occur due to neglecting the treatment of gluten sensitivity, as well as damage to the intestinal villi and the loss of many nutrients and compounds that the body needs to complete its functions. Examples of complications that occur due to gluten sensitivity include:[7][8][9]

  • Lactose intolerance: These are cases in which the body loses the ability to digest and break down the sugar lactose due to the presence of intestinal disorders, as well as bloating, diarrhea and colic.
  • Osteoporosis and osteoporosis: It is a condition that occurs due to the inability of the intestine to absorb calcium, which leads to a decrease in bone mass, and then begins with osteoporosis and may develop into osteoporosis in addition to increasing the rate of fracture.
  • Anemia: Intestinal disorders cause anemia due to iron deficiency, which depends on the intestines for absorption, as there is no way to deliver it to cells when iron is deficient, which leads to an imbalance in red blood cells.
  • Fertility problems: Intestinal disorders delay pregnancy for women and sometimes lead to miscarriage, as these complications are known in celiac disease. In addition, there is a case in which there is an improvement in fertility after treating the symptoms of gluten sensitivity in people who develop gluten sensitivity not related to celiac disease.
  • Nervous system problems: People with celiac disease have neuropathy and problems controlling limb movement called ataxia, as this is due to a lack of vitamins and minerals.
  • Other problems: Because the intestines are unable to communicate with the rest of the body, many people with celiac disease suffer from diseases of the liver, gallbladder, and pancreas.

Gluten sensitivity and mental disorders

One of the symptoms of gluten sensitivity on the body is the presence of some symptoms that affect the nervous system, including headaches, lack of focus and confusion, as these symptoms affect the psyche of the individual, resulting in some psychological disorders, which are as follows:[10]

  • Anxiety and depression: People with intestinal disorder are prone to depression, and researchers have linked nutritional deficiency due to intestinal disorder and high rates of depression and anxiety, and there is a possible hypothesis that there is a direct relationship between gluten and the state of the brain.
  • Schizophrenia and bipolar disorder: Studies have shown high rates of bipolar disorder for people with gluten sensitivity. As for schizophrenia, there are some ideas that believe that schizophrenic patients who are prohibited from eating bread containing gluten will show an improvement in their health.

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Gluten Free Food

Gluten sensitivity can be avoided by working on a diet free of any source of gluten, and there are many foods that do not contain it, the most important of which are the following: [11]

  • the rice.
  • soy;
  • linen;
  • the rice.
  • quinoa;
  • oats;
  • beans;
  • hominy.
  • corn seeds.
  • rye.
  • black wheat.
  • Corn and cornmeal.
  • Unpacked meat.
  • Fresh fruits and vegetables.

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Diagnosing gluten sensitivity

There are many methods that work to diagnose gluten sensitivity, and in the following will be the methods that contribute to the diagnosis of celiac disease and non-celiac gluten sensitivity:

celiac disease

Celiac disease is one of the types of gluten sensitivity that has many methods for diagnosing it, as it differs in its accuracy, sensitivity and principle of action, and it is not possible to fully rely on the symptoms of gluten sensitivity to diagnose the disease. Among these tests that may diagnose celiac disease are the following:[12]

  • Serology Test: It works to determine the amount of antibody to the protein in the blood.
  • Genetic testing: It is done by examining the white blood cell antigens, by which the disease is excluded.
  • Endoscopy test: It is through the use of the endoscope to reach the intestinal wall and take a sample of the intestinal tissue, in order to confirm the presence of damage to the intestinal villi.

Non-celiac gluten sensitivity

The diagnosis of gluten sensitivity that is not related to celiac disease depends on the principle of exception. Or examination of serology, as studies have shown in the presence of anti-gliadin in 50% of cases.[13]

How to treat gluten sensitivity

Gluten sensitivity can be treated in order to relieve symptoms that result from either the gluten sensitivity related to celiac disease or the non-celiac disease gluten sensitivity, as will be explained in the following:

Celiac disease gluten sensitivity treatment

Gluten sensitivity is treated by working to prevent the symptoms of gluten sensitivity from appearing, and this is represented in the following:[14]

  • Refrain from taking medications and foods that contain gluten.
  • Use of some effective medicines, while paying attention to special guidelines.
  • Adopt gluten-free foods.

Non-celiac gluten sensitivity treatment

The primary treatment method that is adopted in such cases is similar to the treatment of digestive disorders, and it is as follows:[15]

  • Avoid eating foods that contain gluten, as it is considered a successful method in all types of gluten sensitivity.
  • Not taking nutritional supplements, as they harm the intestines, and thus contribute to the proper absorption of nutrients and not being affected.

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Other conditions related to gluten

Some symptoms of gluten sensitivity do not appear due to the two cases of celiac disease and non-related gluten sensitivity in celiac disease, as there is a new distribution of disorders related to gluten, and these cases can be divided according to the mechanism of the disease into three mechanisms, which are as follows:[16]

  • Diseases caused by allergic reactions: It includes symptoms related to wheat allergy, as it includes many disorders such as: respiratory system allergy and food allergy.
  • Autoimmune diseases: These include gastrointestinal disturbances, gluten ataxia, and dermatitis herpetiformis.
  • Diseases of unknown etiology: One such disease is gluten sensitivity, which is not related to celiac disease.

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Thus, we have come to the end of this article, which was titled What is gluten sensitivity?After we have attached to you the definition of gluten and its health importance, the symptoms and causes of gluten sensitivity and the most prominent complications that occur when suffering from gluten sensitivity were also discussed.

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